test: ( SearchWords LIKE '%University%' AND SearchWords LIKE '%of%' AND SearchWords LIKE '%California,%' AND SearchWords LIKE '%Berkeley%' )
SELECT COUNT(*) FROM ipnavigate.Dockets AS d, ipnavigate.ResearchFirms AS rf WHERE d.ResearchFirmID=rf.ID AND ( ( SearchWords LIKE '%University%' AND SearchWords LIKE '%of%' AND SearchWords LIKE '%California,%' AND SearchWords LIKE '%Berkeley%' ) )
|
University of California, Berkeley
|
2D and 3D Plasma Modeling
|
|
|
The XOOPIC code suite is a set of particle-in-cell plasma simulation codes for modeling plasmas in two and three dimensions. XOOPIC includes electrostatic and electromagnetic models, collision models for mixtures of noble gases, and a wide range of boundary conditions which can be specified from an input file without recompiling.XOOPIC can be used to simulate basic plasma phenomena, microwave-beam...
|
 |
|
|
|
|
University of California, Berkeley
|
2D and 3D Plasma Modeling
|
|
|
The XOOPIC code suite is a set of particle-in-cell plasma simulation codes for modeling plasmas in two and three dimensions. XOOPIC includes electrostatic and electromagnetic models, collision models for mixtures of noble gases, and a wide range of boundary conditions which can be specified from an input file without recompiling.XOOPIC can be used to simulate basic plasma phenomena, microwave-beam...
|
 |
|
|
|
|
University of California, Berkeley
|
3D Model Generation for Urban Environments
|
|
|
Three-dimensional photo realistic models of urban environments that can be used for simulation and interactive fly-thrus are useful in a growing variety of applications such as urban planning, disaster training, virtual heritage conservation, and Internet-based consumer services. However, previous methods for producing these images were slow and required enormous amounts of manual work -- conseque...
|
 |
|
|
|
|
University of California, Berkeley
|
3D Model Generation for Urban Environments
|
|
|
Three-dimensional photo realistic models of urban environments that can be used for simulation and interactive fly-thrus are useful in a growing variety of applications such as urban planning, disaster training, virtual heritage conservation, and Internet-based consumer services. However, previous methods for producing these images were slow and required enormous amounts of manual work -- conseque...
|
 |
|
|
|
|
University of California, Berkeley
|
51 BLim 10 Tumor Cell Line
|
|
|
A variety of tumors are potentially immunogenic but do not stimulate an effective anti-tumor immune response in vivo. Tumors may be capable of delivering antigen-specific signals to T cells, but may not deliver the costimulatory signals necessary for full activation of T cells. Expression of the costimulatory ligand B7 on melanoma cells was found to induce the rejection of a murine melanoma in viv...
|
 |
|
|
|
|
University of California, Berkeley
|
A Genetic Pathway for Serotonin Signaling
|
|
|
Currently there is no abstract assigned to this invention. If you would like more information about this invention please contact the Licensing Officer listed below....
|
 |
|
|
|
|
University of California, Berkeley
|
A Genetic Pathway for Serotonin Signaling
|
|
|
Currently there is no abstract assigned to this invention. If you would like more information about this invention please contact the Licensing Officer listed below....
|
 |
|
|
|
|
University of California, Berkeley
|
A Genetically Encoded Optical Probe of MembraneVoltage
|
|
|
Measuring electrical activity in large numbers of cells with high spatial and temporal resolution is a fundamental problem for the study of neural development and information processing. To address this problem, researchers at UC Berkeley have constructed a novel, genetically encoded probe that can be used to measure transmembrane voltage in single cells. A modified green fluorescent protein (GFP)...
|
 |
|
|
|
|
University of California, Berkeley
|
A Method for Forming Double-Gate Metal Oxide Semiconductor Field Effect Transistors
|
|
|
Metal Oxide Semiconductor field effect transistor (MOSFET) technology is the dominant electronic device technology in use today. Performance enhancement is achieved primarily by device scaling. However, as MOSFETs are scaled to channel lengths below 100nm, conventional devices suffer from problems such as short channel effects and reduced gate control. A double gate MOSFET device allows gate contr...
|
 |
|
|
|
|
University of California, Berkeley
|
A Mutant of the Green Alga Dunaliella salina Accumulates Zeaxanthin, a High-Value Bio-Product
|
|
|
A novel mutant of of the halotolerant unicellular green alga Dunaliella salinia lacks a number of the beta-branch xanthophylls but accumulates zeaxanthin. Biochemical analysis suggests that zeaxanthin substitutes for the beta-branched xanthophylls in the mutant strain. This mutant may provide a biological source for the production of zeaxanthin, a high value bio-product.Ref.: E. Jin, & et al. ...
|
 |
|
|
|
|
University of California, Berkeley
|
A new approach to flow cytometry, "NanoCytometry"
|
|
|
Conventional flow cytometry has made valuable contributions to cancer diagnosis and management as well as to the understanding of fundamental cancer cell biology. Flow cytometry is used routinely in the clinical diagnosis of the hematologic malignancies; in tumor immunology to define lymphocyte subsets; and in basic research to facilitate cell separations based on the expression of particular prot...
|
 |
|
|
|
|
University of California, Berkeley
|
A new approach to flow cytometry, "NanoCytometry"
|
|
|
Conventional flow cytometry has made valuable contributions to cancer diagnosis and management as well as to the understanding of fundamental cancer cell biology. Flow cytometry is used routinely in the clinical diagnosis of the hematologic malignancies; in tumor immunology to define lymphocyte subsets; and in basic research to facilitate cell separations based on the expression of particular prot...
|
 |
|
|
|
|
University of California, Berkeley
|
A new approach to flow cytometry, "NanoCytometry"
|
|
|
Conventional flow cytometry has made valuable contributions to cancer diagnosis and management as well as to the understanding of fundamental cancer cell biology. Flow cytometry is used routinely in the clinical diagnosis of the hematologic malignancies; in tumor immunology to define lymphocyte subsets; and in basic research to facilitate cell separations based on the expression of particular prot...
|
 |
|
|
|
|
University of California, Berkeley
|
A new approach to flow cytometry, "NanoCytometry"
|
|
|
Conventional flow cytometry has made valuable contributions to cancer diagnosis and management as well as to the understanding of fundamental cancer cell biology. Flow cytometry is used routinely in the clinical diagnosis of the hematologic malignancies; in tumor immunology to define lymphocyte subsets; and in basic research to facilitate cell separations based on the expression of particular prot...
|
 |
|
|
|
|
University of California, Berkeley
|
A New Architecture For a Field Programmable Logic Device
|
|
|
A Programmable Logic Device (PLD) is an integrated circuit that can be programmed to perform complex logic functions. It consists of arrays of AND and OR gates. A mask-programmable logic device is programmed through the process of fabricating the device. In contrast, a Field programmable Logic Device (FPLD) is distributed by the manufacturer in an unprogrammed state, and is to be programmed "in th...
|
 |
|
|
|
|
University of California, Berkeley
|
A New Architecture For a Field Programmable Logic Device
|
|
|
A Programmable Logic Device (PLD) is an integrated circuit that can be programmed to perform complex logic functions. It consists of arrays of AND and OR gates. A mask-programmable logic device is programmed through the process of fabricating the device. In contrast, a Field programmable Logic Device (FPLD) is distributed by the manufacturer in an unprogrammed state, and is to be programmed "in th...
|
 |
|
|
|
|
University of California, Berkeley
|
A New Corneal Preservation Solution
|
|
|
Research at the University of California, Berkeley has resulted in the formulation of a new medium for the preservation of cellular tissues. The new tissue preservation medium is based on fundamental physiological principles and on research findings from UC Berkeley regarding maintenance of cell membrane integrity. The understanding of the mechanism of cell membranes showed that repair normally re...
|
 |
|
|
|
|
University of California, Berkeley
|
A New Process for Biomolecule Patterning
|
|
|
Patterning of biomolecules is important in areas like biological analysis, diagnostics and genomics. In addition, molecular patterning could be useful for spatial control of various surface properties such as hydrophobicity and surface charge.Currently, molecules are patterned using lithography, stamping, or using scanning tips. Lithography requires either specially synthesized light-sensitive mol...
|
 |
|
|
|
|
University of California, Berkeley
|
A New Process for Biomolecule Patterning
|
|
|
Patterning of biomolecules is important in areas like biological analysis, diagnostics and genomics. In addition, molecular patterning could be useful for spatial control of various surface properties such as hydrophobicity and surface charge.Currently, molecules are patterned using lithography, stamping, or using scanning tips. Lithography requires either specially synthesized light-sensitive mol...
|
 |
|
|
|
|
University of California, Berkeley
|
A New Process for Biomolecule Patterning
|
|
|
Patterning of biomolecules is important in areas like biological analysis, diagnostics and genomics. In addition, molecular patterning could be useful for spatial control of various surface properties such as hydrophobicity and surface charge.Currently, molecules are patterned using lithography, stamping, or using scanning tips. Lithography requires either specially synthesized light-sensitive mol...
|
 |
|
|
|
|
University of California, Berkeley
|
A New Process for Biomolecule Patterning
|
|
|
Patterning of biomolecules is important in areas like biological analysis, diagnostics and genomics. In addition, molecular patterning could be useful for spatial control of various surface properties such as hydrophobicity and surface charge.Currently, molecules are patterned using lithography, stamping, or using scanning tips. Lithography requires either specially synthesized light-sensitive mol...
|
 |
|
|
|
|
University of California, Berkeley
|
A New Process for Biomolecule Patterning
|
|
|
Patterning of biomolecules is important in areas like biological analysis, diagnostics and genomics. In addition, molecular patterning could be useful for spatial control of various surface properties such as hydrophobicity and surface charge.Currently, molecules are patterned using lithography, stamping, or using scanning tips. Lithography requires either specially synthesized light-sensitive mol...
|
 |
|
|
|
|
University of California, Berkeley
|
A New Process for Biomolecule Patterning
|
|
|
Patterning of biomolecules is important in areas like biological analysis, diagnostics and genomics. In addition, molecular patterning could be useful for spatial control of various surface properties such as hydrophobicity and surface charge.Currently, molecules are patterned using lithography, stamping, or using scanning tips. Lithography requires either specially synthesized light-sensitive mol...
|
 |
|
|
|
|
University of California, Berkeley
|
A NOVEL STRESS-TOLERANCE PROTEIN
|
|
|
Drought, cold, and salinity are environmental factors that can limit crop productivity worldwide. in response to these stresses, plants mount a number of defense reactions that increase the tolerance to the stress. Scientists at UC Berkeley have recently isolated a plant gene encoding a novel protein which functions as a signaling molecule in the stress signal transduction pathway. Expression of t...
|
 |
|
|
|
|
University of California, Berkeley
|
A NOVEL STRESS-TOLERANCE PROTEIN
|
|
|
Drought, cold, and salinity are environmental factors that can limit crop productivity worldwide. in response to these stresses, plants mount a number of defense reactions that increase the tolerance to the stress. Scientists at UC Berkeley have recently isolated a plant gene encoding a novel protein which functions as a signaling molecule in the stress signal transduction pathway. Expression of t...
|
 |
|
|
|
|
University of California, Berkeley
|
A Site-Specific Endonuclease for the Cleavage of Very Large DNA Molecules
|
|
|
A DNA endonuclease, VDE, is derived from the yeast Sacchromyces cerevisiae and is related to other nucleases involvled in nucleic acid rearrangements. Analysis shows that VDE recognizes an extended sequence: TATSYATGYYGGGTGY|GGRGAARKMGKKAAWGAAAWG, and leaves a staggered double-strand break with 4-bp 3'-hydroxyl overhangs.References:Bremer et al. 1992. Nuc. Acid Res. 20:5484Gimble et al. 1993 J. Bi...
|
 |
|
|
|
|
University of California, Berkeley
|
A Site-Specific Endonuclease for the Cleavage of Very Large DNA Molecules
|
|
|
A DNA endonuclease, VDE, is derived from the yeast Sacchromyces cerevisiae and is related to other nucleases involvled in nucleic acid rearrangements. Analysis shows that VDE recognizes an extended sequence: TATSYATGYYGGGTGY|GGRGAARKMGKKAAWGAAAWG, and leaves a staggered double-strand break with 4-bp 3'-hydroxyl overhangs.References:Bremer et al. 1992. Nuc. Acid Res. 20:5484Gimble et al. 1993 J. Bi...
|
 |
|
|
|
|
University of California, Berkeley
|
A UNIVERSAL, LIGHT-SWITCHABLE GENE PROMOTER SYSTEM
|
|
|
Synopsis:This invention consists of an artificial promoter system that can be fused upstream of any desired gene, enabling reversible and light-switchable induction or repression of gene expression in any suitable host cell.New data to be filed in a provisional patent application demonstrates optimized expression conditionsand a "switching off" mechanism in addition to the "switching on" mechanism...
|
 |
|
|
|
|
University of California, Berkeley
|
A UNIVERSAL, LIGHT-SWITCHABLE GENE PROMOTER SYSTEM
|
|
|
Synopsis:This invention consists of an artificial promoter system that can be fused upstream of any desired gene, enabling reversible and light-switchable induction or repression of gene expression in any suitable host cell.New data to be filed in a provisional patent application demonstrates optimized expression conditionsand a "switching off" mechanism in addition to the "switching on" mechanism...
|
 |
|
|
|
|
University of California, Berkeley
|
A UNIVERSAL, LIGHT-SWITCHABLE GENE PROMOTER SYSTEM
|
|
|
Synopsis:This invention consists of an artificial promoter system that can be fused upstream of any desired gene, enabling reversible and light-switchable induction or repression of gene expression in any suitable host cell.New data to be filed in a provisional patent application demonstrates optimized expression conditionsand a "switching off" mechanism in addition to the "switching on" mechanism...
|
 |
|
|
|
|
University of California, Berkeley
|
A UNIVERSAL, LIGHT-SWITCHABLE GENE PROMOTER SYSTEM
|
|
|
Synopsis:This invention consists of an artificial promoter system that can be fused upstream of any desired gene, enabling reversible and light-switchable induction or repression of gene expression in any suitable host cell.New data to be filed in a provisional patent application demonstrates optimized expression conditionsand a "switching off" mechanism in addition to the "switching on" mechanism...
|
 |
|
|
|
|
University of California, Berkeley
|
Active Frequency Tuning of Thin-Film Bulk Acoustic Wave Resonators
|
|
|
High quality factor resonators that function as band and channel select filters, and oscillator feedback elements are indispensable components in many modern wireless transceivers. Surface acoustic wave devices (SAWs) and dielectric resonators have dominated the market for these components. However, the maximum frequency of operation, minimum insertion loss, power handling, and form factor of thes...
|
 |
|
|
|
|
University of California, Berkeley
|
Adaptive Exercise Machine
|
|
|
Researchers at the University of California, Berkeley, have developed an apparatus and method for controlling the torque of an exercise machine. The invention determines the torque which the user is able to exert at different positions and velocities, and develops a strength model of the user. Based on the strength model of the user, the invention determines a desired velocity profile for the user...
|
 |
|
|
|
|
University of California, Berkeley
|
Adaptive Exercise Machine
|
|
|
Researchers at the University of California, Berkeley, have developed an apparatus and method for controlling the torque of an exercise machine. The invention determines the torque which the user is able to exert at different positions and velocities, and develops a strength model of the user. Based on the strength model of the user, the invention determines a desired velocity profile for the user...
|
 |
|
|
|
|
University of California, Berkeley
|
Adjustable Resonance Generator Powered by Environmental Vibration
|
|
|
As the microelectronics industry continues to reduce the size and power attributes of communication, sensor and mechanical electronics, there is an increasing need to power these devices over their life-span with an inexpensive, no-maintenance, renewable energy source that has compatible fabrication technology. One alternative, vibration energy scavenging is emerging as a viable power source for t...
|
 |
|
|
|
|
University of California, Berkeley
|
Adjustable Resonance Generator Powered by Environmental Vibration
|
|
|
As the microelectronics industry continues to reduce the size and power attributes of communication, sensor and mechanical electronics, there is an increasing need to power these devices over their life-span with an inexpensive, no-maintenance, renewable energy source that has compatible fabrication technology. One alternative, vibration energy scavenging is emerging as a viable power source for t...
|
 |
|
|
|
|
University of California, Berkeley
|
Adjustable Resonance Generator Powered by Environmental Vibration
|
|
|
As the microelectronics industry continues to reduce the size and power attributes of communication, sensor and mechanical electronics, there is an increasing need to power these devices over their life-span with an inexpensive, no-maintenance, renewable energy source that has compatible fabrication technology. One alternative, vibration energy scavenging is emerging as a viable power source for t...
|
 |
|
|
|
|
University of California, Berkeley
|
Adjustable Resonance Generator Powered by Environmental Vibration
|
|
|
As the microelectronics industry continues to reduce the size and power attributes of communication, sensor and mechanical electronics, there is an increasing need to power these devices over their life-span with an inexpensive, no-maintenance, renewable energy source that has compatible fabrication technology. One alternative, vibration energy scavenging is emerging as a viable power source for t...
|
 |
|
|
|
|
University of California, Berkeley
|
AFC1 And RCE1: Isoprenylated CAAX Processing Enzymes
|
|
|
See also: Rine, J. et. al., "Modulation of Ras and a-Factor Functio by Caroxyl-Terminal Proteolysis," Science, Vol. 275, March 21, 1997, pp. 1796 - 1800.Two genes which encode polypeptides that mediate post-prenylation processing steps in CAAX polypeptides such as Ras are provided. The two genes (AFC1 and RCE1) encode polypeptides that mediate the removal of the AAX tripeptide from the CAAX polype...
|
 |
|
|
|
|
University of California, Berkeley
|
An Automated System For Three-Dimensional Histological Imaging
|
|
|
Researchers at the University of California, Berkeley have developed an automated three-dimensional imaging system that provides an efficient, high-resolution method of creating complete volumetric reconstructions of biological tissues containing histological information in the form of fluorochrome labels.Alternatively, samples may be individually processed by the automated system using a histolog...
|
 |
|
|
|
|
University of California, Berkeley
|
An Automated System For Three-Dimensional Histological Imaging
|
|
|
Researchers at the University of California, Berkeley have developed an automated three-dimensional imaging system that provides an efficient, high-resolution method of creating complete volumetric reconstructions of biological tissues containing histological information in the form of fluorochrome labels.Alternatively, samples may be individually processed by the automated system using a histolog...
|
 |
|
|
|
|
University of California, Berkeley
|
An Automated System For Three-Dimensional Histological Imaging
|
|
|
Researchers at the University of California, Berkeley have developed an automated three-dimensional imaging system that provides an efficient, high-resolution method of creating complete volumetric reconstructions of biological tissues containing histological information in the form of fluorochrome labels.Alternatively, samples may be individually processed by the automated system using a histolog...
|
 |
|
|
|
|
University of California, Berkeley
|
An Automated System For Three-Dimensional Histological Imaging
|
|
|
Researchers at the University of California, Berkeley have developed an automated three-dimensional imaging system that provides an efficient, high-resolution method of creating complete volumetric reconstructions of biological tissues containing histological information in the form of fluorochrome labels.Alternatively, samples may be individually processed by the automated system using a histolog...
|
 |
|
|
|
|
University of California, Berkeley
|
An Automated System For Three-Dimensional Histological Imaging
|
|
|
Researchers at the University of California, Berkeley have developed an automated three-dimensional imaging system that provides an efficient, high-resolution method of creating complete volumetric reconstructions of biological tissues containing histological information in the form of fluorochrome labels.Alternatively, samples may be individually processed by the automated system using a histolog...
|
 |
|
|
|
|
University of California, Berkeley
|
An Automated System For Three-Dimensional Histological Imaging
|
|
|
Researchers at the University of California, Berkeley have developed an automated three-dimensional imaging system that provides an efficient, high-resolution method of creating complete volumetric reconstructions of biological tissues containing histological information in the form of fluorochrome labels.Alternatively, samples may be individually processed by the automated system using a histolog...
|
 |
|
|
|
|
University of California, Berkeley
|
An Inexpensive and Highly Sensitive, Micromachined Pressure Sensor Device
|
|
|
Micromachined pressure sensors are important for biomedical, automotive, and lab-on-a-chip applications. Most sensors are based either on capacitance changes across a Si cavity or resistance changes in piezoresistive materials as a response to applied pressure.Researchers at the University of California, Berkeley have developed a new type of pressure sensor based on a new mechanical design. The se...
|
 |
|
|
|
|
University of California, Berkeley
|
An Inexpensive and Highly Sensitive, Micromachined Pressure Sensor Device
|
|
|
Micromachined pressure sensors are important for biomedical, automotive, and lab-on-a-chip applications. Most sensors are based either on capacitance changes across a Si cavity or resistance changes in piezoresistive materials as a response to applied pressure.Researchers at the University of California, Berkeley have developed a new type of pressure sensor based on a new mechanical design. The se...
|
 |
|
|
|
|
University of California, Berkeley
|
An Inexpensive and Highly Sensitive, Micromachined Pressure Sensor Device
|
|
|
Micromachined pressure sensors are important for biomedical, automotive, and lab-on-a-chip applications. Most sensors are based either on capacitance changes across a Si cavity or resistance changes in piezoresistive materials as a response to applied pressure.Researchers at the University of California, Berkeley have developed a new type of pressure sensor based on a new mechanical design. The se...
|
 |
|
|
|
|
University of California, Berkeley
|
An Inexpensive and Highly Sensitive, Micromachined Pressure Sensor Device
|
|
|
Micromachined pressure sensors are important for biomedical, automotive, and lab-on-a-chip applications. Most sensors are based either on capacitance changes across a Si cavity or resistance changes in piezoresistive materials as a response to applied pressure.Researchers at the University of California, Berkeley have developed a new type of pressure sensor based on a new mechanical design. The se...
|
 |
|
|
|
|
University of California, Berkeley
|
An Inexpensive and Highly Sensitive, Micromachined Pressure Sensor Device
|
|
|
Micromachined pressure sensors are important for biomedical, automotive, and lab-on-a-chip applications. Most sensors are based either on capacitance changes across a Si cavity or resistance changes in piezoresistive materials as a response to applied pressure.Researchers at the University of California, Berkeley have developed a new type of pressure sensor based on a new mechanical design. The se...
|
 |
|
|
|
|
University of California, Berkeley
|
An Inexpensive and Highly Sensitive, Micromachined Pressure Sensor Device
|
|
|
Micromachined pressure sensors are important for biomedical, automotive, and lab-on-a-chip applications. Most sensors are based either on capacitance changes across a Si cavity or resistance changes in piezoresistive materials as a response to applied pressure.Researchers at the University of California, Berkeley have developed a new type of pressure sensor based on a new mechanical design. The se...
|
 |
|
|
|
|
University of California, Berkeley
|
Analytical Methods and Test Structures for Measuring Properties of Micro- and Nano- Scale Systems
|
|
|
As micro- and nano-scale electromechanical systems become commercially established, the widespread success of these products will be hindered unless testing methods and standards are developed to measure the properties of these products. Currently, the lack of testing methods and standards makes it difficult for customers to specify their requirements, and manufacturers to specify the properties o...
|
 |
|
|
|
|
University of California, Berkeley
|
Analytical Methods and Test Structures for Measuring Properties of Micro- and Nano- Scale Systems
|
|
|
As micro- and nano-scale electromechanical systems become commercially established, the widespread success of these products will be hindered unless testing methods and standards are developed to measure the properties of these products. Currently, the lack of testing methods and standards makes it difficult for customers to specify their requirements, and manufacturers to specify the properties o...
|
 |
|
|
|
|
University of California, Berkeley
|
Analytical Methods and Test Structures for Measuring Properties of Micro- and Nano- Scale Systems
|
|
|
As micro- and nano-scale electromechanical systems become commercially established, the widespread success of these products will be hindered unless testing methods and standards are developed to measure the properties of these products. Currently, the lack of testing methods and standards makes it difficult for customers to specify their requirements, and manufacturers to specify the properties o...
|
 |
|
|
|
|
University of California, Berkeley
|
Analytical Methods and Test Structures for Measuring Properties of Micro- and Nano- Scale Systems
|
|
|
As micro- and nano-scale electromechanical systems become commercially established, the widespread success of these products will be hindered unless testing methods and standards are developed to measure the properties of these products. Currently, the lack of testing methods and standards makes it difficult for customers to specify their requirements, and manufacturers to specify the properties o...
|
 |
|
|
|
|
University of California, Berkeley
|
Axial Light-Force Sensor
|
|
|
Commercially available optical tweezers can move objects using laser light, but they are generally not used to measure forces exerted on those objects, since accurate force calibration is difficult. Research in the field of optical trapping has led to the development of optical tweezers that measure forces (transverse to optic axis) by changes in light-momentum. Force calibration is greatly simpli...
|
 |
|
|
|
|
University of California, Berkeley
|
Axial Light-Force Sensor
|
|
|
Commercially available optical tweezers can move objects using laser light, but they are generally not used to measure forces exerted on those objects, since accurate force calibration is difficult. Research in the field of optical trapping has led to the development of optical tweezers that measure forces (transverse to optic axis) by changes in light-momentum. Force calibration is greatly simpli...
|
 |
|
|
|
|
University of California, Berkeley
|
Axial Light-Force Sensor
|
|
|
Commercially available optical tweezers can move objects using laser light, but they are generally not used to measure forces exerted on those objects, since accurate force calibration is difficult. Research in the field of optical trapping has led to the development of optical tweezers that measure forces (transverse to optic axis) by changes in light-momentum. Force calibration is greatly simpli...
|
 |
|
|
|
|
University of California, Berkeley
|
Axial Light-Force Sensor
|
|
|
Commercially available optical tweezers can move objects using laser light, but they are generally not used to measure forces exerted on those objects, since accurate force calibration is difficult. Research in the field of optical trapping has led to the development of optical tweezers that measure forces (transverse to optic axis) by changes in light-momentum. Force calibration is greatly simpli...
|
 |
|
|
|
|
University of California, Berkeley
|
Axial Light-Force Sensor
|
|
|
Commercially available optical tweezers can move objects using laser light, but they are generally not used to measure forces exerted on those objects, since accurate force calibration is difficult. Research in the field of optical trapping has led to the development of optical tweezers that measure forces (transverse to optic axis) by changes in light-momentum. Force calibration is greatly simpli...
|
 |
|
|
|
|
University of California, Berkeley
|
Axial Light-Force Sensor
|
|
|
Commercially available optical tweezers can move objects using laser light, but they are generally not used to measure forces exerted on those objects, since accurate force calibration is difficult. Research in the field of optical trapping has led to the development of optical tweezers that measure forces (transverse to optic axis) by changes in light-momentum. Force calibration is greatly simpli...
|
 |
|
|
|
|
University of California, Berkeley
|
Axial Light-Force Sensor
|
|
|
Commercially available optical tweezers can move objects using laser light, but they are generally not used to measure forces exerted on those objects, since accurate force calibration is difficult. Research in the field of optical trapping has led to the development of optical tweezers that measure forces (transverse to optic axis) by changes in light-momentum. Force calibration is greatly simpli...
|
 |
|
|
|
|
University of California, Berkeley
|
Axial Light-Force Sensor
|
|
|
Commercially available optical tweezers can move objects using laser light, but they are generally not used to measure forces exerted on those objects, since accurate force calibration is difficult. Research in the field of optical trapping has led to the development of optical tweezers that measure forces (transverse to optic axis) by changes in light-momentum. Force calibration is greatly simpli...
|
 |
|
|
|
|
University of California, Berkeley
|
Bandwidth Improvement and Distortion Reduction in Closed-Box Loudspeaker Systems
|
|
|
Using novel feedback sensing techniques, and a control algorithm (together referred to as "the control system"), researchers at the University of California, Berkeley, have expanded the bandwidth of a professional grade low-frequency transducer, while simultaneously reducing the distortion. The unique idea is that the control system is physically independent of the loudspeaker, allowing the introd...
|
 |
|
|
|
|
University of California, Berkeley
|
Batch Fabrication of Devices with Nano Wires and Nano Gaps
|
|
|
Low cost, high volume batch fabrication of electromechanical resonators can't scale below 10 micrometers using current technology; and non-batch methods for fabricating these devices at the nano-scale are tedious and uneconomical. These non-batch methods require the nano resonators to be fabricated individually because the methods can't control the location of nanowires and the electrodes can't be...
|
 |
|
|
|
|
University of California, Berkeley
|
Batch Fabrication of Devices with Nano Wires and Nano Gaps
|
|
|
Low cost, high volume batch fabrication of electromechanical resonators can't scale below 10 micrometers using current technology; and non-batch methods for fabricating these devices at the nano-scale are tedious and uneconomical. These non-batch methods require the nano resonators to be fabricated individually because the methods can't control the location of nanowires and the electrodes can't be...
|
 |
|
|
|
|
University of California, Berkeley
|
Batch-Processed Magnetic Microactuators
|
|
|
This batch-processed MEMS device features a large magnetically actuated force that is electrostatically addressed. It facilitates microstructures with high areal density and increased design flexibility. Also, its torsional flexure structure constrains motion to rotation about a single axis - which is ideal for various applications including micromirror systems as well as optical scanners, display...
|
 |
|
|
|
|
University of California, Berkeley
|
Batch-Processed Magnetic Microactuators
|
|
|
This batch-processed MEMS device features a large magnetically actuated force that is electrostatically addressed. It facilitates microstructures with high areal density and increased design flexibility. Also, its torsional flexure structure constrains motion to rotation about a single axis - which is ideal for various applications including micromirror systems as well as optical scanners, display...
|
 |
|
|
|
|
University of California, Berkeley
|
Behavioral Synthesis for Reconfigurable Datapath Structures
|
|
|
High level synthesis of datapaths has traditionally concentrated on synthesizing a specific implementation for a given computational problem. This invention involves methods to compose a reconfigurable BISR (built-in-self repair) implementation with a minimum amount of area overhead. Previously the BISR scope has been restricted to the substitution of operation modules with only those of the same ...
|
 |
|
|
|
|
University of California, Berkeley
|
BERYLLOFLUORIDE MIMICS THE ACYL PHOSPHATE LINKAGE IN BACTERIAL 'RECEIVER' DOMAINS
|
|
|
Two-component systems (sensor kinase-response regulator pairs) dominate bacterial signal transduction. Regulation is exerted by phosphorylation of an aspartate residue in receiver domains of response regulators. Lability of the acyl phosphate linkage has limited the structural characterization of active, phosphorylated forms of receiver domains. This invention features methods and compositions for...
|
 |
|
|
|
|
University of California, Berkeley
|
BERYLLOFLUORIDE MIMICS THE ACYL PHOSPHATE LINKAGE IN BACTERIAL 'RECEIVER' DOMAINS
|
|
|
Two-component systems (sensor kinase-response regulator pairs) dominate bacterial signal transduction. Regulation is exerted by phosphorylation of an aspartate residue in receiver domains of response regulators. Lability of the acyl phosphate linkage has limited the structural characterization of active, phosphorylated forms of receiver domains. This invention features methods and compositions for...
|
 |
|
|
|
|
University of California, Berkeley
|
BERYLLOFLUORIDE MIMICS THE ACYL PHOSPHATE LINKAGE IN BACTERIAL 'RECEIVER' DOMAINS
|
|
|
Two-component systems (sensor kinase-response regulator pairs) dominate bacterial signal transduction. Regulation is exerted by phosphorylation of an aspartate residue in receiver domains of response regulators. Lability of the acyl phosphate linkage has limited the structural characterization of active, phosphorylated forms of receiver domains. This invention features methods and compositions for...
|
 |
|
|
|
|
University of California, Berkeley
|
Biocompatible Nanostructures for Ultrasensitive Biomolecular Sensors and Cellular Imaging
|
|
|
A variety of nanostructures have been developed for use in biomolecular detection. The nanosphere is the most widely used structure because of unique, highly desirable properties that make it a superior detection platform for life science research, in vitro diagnostic testing, and in vivo imaging. Other structures such as nanotips, nanorings, and nanocups have also been demonstrated for use in hig...
|
 |
|
|
|
|
University of California, Berkeley
|
Biocompatible Nanostructures for Ultrasensitive Biomolecular Sensors and Cellular Imaging
|
|
|
A variety of nanostructures have been developed for use in biomolecular detection. The nanosphere is the most widely used structure because of unique, highly desirable properties that make it a superior detection platform for life science research, in vitro diagnostic testing, and in vivo imaging. Other structures such as nanotips, nanorings, and nanocups have also been demonstrated for use in hig...
|
 |
|
|
|
|
University of California, Berkeley
|
Biocompatible Nanostructures for Ultrasensitive Biomolecular Sensors and Cellular Imaging
|
|
|
A variety of nanostructures have been developed for use in biomolecular detection. The nanosphere is the most widely used structure because of unique, highly desirable properties that make it a superior detection platform for life science research, in vitro diagnostic testing, and in vivo imaging. Other structures such as nanotips, nanorings, and nanocups have also been demonstrated for use in hig...
|
 |
|
|
|
|
University of California, Berkeley
|
Biocompatible Nanostructures for Ultrasensitive Biomolecular Sensors and Cellular Imaging
|
|
|
A variety of nanostructures have been developed for use in biomolecular detection. The nanosphere is the most widely used structure because of unique, highly desirable properties that make it a superior detection platform for life science research, in vitro diagnostic testing, and in vivo imaging. Other structures such as nanotips, nanorings, and nanocups have also been demonstrated for use in hig...
|
 |
|
|
|
|
University of California, Berkeley
|
Biocompatible Nanostructures for Ultrasensitive Biomolecular Sensors and Cellular Imaging
|
|
|
A variety of nanostructures have been developed for use in biomolecular detection. The nanosphere is the most widely used structure because of unique, highly desirable properties that make it a superior detection platform for life science research, in vitro diagnostic testing, and in vivo imaging. Other structures such as nanotips, nanorings, and nanocups have also been demonstrated for use in hig...
|
 |
|
|
|
|
University of California, Berkeley
|
Biocompatible Nanostructures for Ultrasensitive Biomolecular Sensors and Cellular Imaging
|
|
|
A variety of nanostructures have been developed for use in biomolecular detection. The nanosphere is the most widely used structure because of unique, highly desirable properties that make it a superior detection platform for life science research, in vitro diagnostic testing, and in vivo imaging. Other structures such as nanotips, nanorings, and nanocups have also been demonstrated for use in hig...
|
 |
|
|
|
|
University of California, Berkeley
|
Biocompatible Nanostructures for Ultrasensitive Biomolecular Sensors and Cellular Imaging
|
|
|
A variety of nanostructures have been developed for use in biomolecular detection. The nanosphere is the most widely used structure because of unique, highly desirable properties that make it a superior detection platform for life science research, in vitro diagnostic testing, and in vivo imaging. Other structures such as nanotips, nanorings, and nanocups have also been demonstrated for use in hig...
|
 |
|
|
|
|
University of California, Berkeley
|
Biologically-Inspired Piezoelectric Gyroscope
|
|
|
Using micromachined gyroscopes to measure angular velocity is becoming increasingly common in applications ranging from ballistics and crash-testing to mobile micro-robotics. Although a variety of MEMS gyroscopes are commercially available, their dynamic range, power requirements and package size are sometimes not well-suited to the applications.To address these problems, researchers at the Univer...
|
 |
|
|
|
|
University of California, Berkeley
|
Biologically-Inspired Piezoelectric Gyroscope
|
|
|
Using micromachined gyroscopes to measure angular velocity is becoming increasingly common in applications ranging from ballistics and crash-testing to mobile micro-robotics. Although a variety of MEMS gyroscopes are commercially available, their dynamic range, power requirements and package size are sometimes not well-suited to the applications.To address these problems, researchers at the Univer...
|
 |
|
|
|
|
University of California, Berkeley
|
Biologically-Inspired Piezoelectric Gyroscope
|
|
|
Using micromachined gyroscopes to measure angular velocity is becoming increasingly common in applications ranging from ballistics and crash-testing to mobile micro-robotics. Although a variety of MEMS gyroscopes are commercially available, their dynamic range, power requirements and package size are sometimes not well-suited to the applications.To address these problems, researchers at the Univer...
|
 |
|
|
|
|
University of California, Berkeley
|
Biologically-Inspired Piezoelectric Gyroscope
|
|
|
Using micromachined gyroscopes to measure angular velocity is becoming increasingly common in applications ranging from ballistics and crash-testing to mobile micro-robotics. Although a variety of MEMS gyroscopes are commercially available, their dynamic range, power requirements and package size are sometimes not well-suited to the applications.To address these problems, researchers at the Univer...
|
 |
|
|
|
|
University of California, Berkeley
|
BioMEMS Immunoassay Platform for In-Field Diagnostics
|
|
|
The rapid diagnosis of infectious diseases is critical for quick containment and effective treatment. The dominant diagnostics technology, ELISA, is cost-effective for diagnosing diseases in a hospital or doctor's office with a laboratory and trained staff. However, ELISA is not a practical solution for the rapid, precise diagnosis of infectious diseases in-the-field.To address this problem, resea...
|
 |
|
|
|
|
University of California, Berkeley
|
BioMEMS Immunoassay Platform for In-Field Diagnostics
|
|
|
The rapid diagnosis of infectious diseases is critical for quick containment and effective treatment. The dominant diagnostics technology, ELISA, is cost-effective for diagnosing diseases in a hospital or doctor's office with a laboratory and trained staff. However, ELISA is not a practical solution for the rapid, precise diagnosis of infectious diseases in-the-field.To address this problem, resea...
|
 |
|
|
|
|
University of California, Berkeley
|
BioMEMS Immunoassay Platform for In-Field Diagnostics
|
|
|
The rapid diagnosis of infectious diseases is critical for quick containment and effective treatment. The dominant diagnostics technology, ELISA, is cost-effective for diagnosing diseases in a hospital or doctor's office with a laboratory and trained staff. However, ELISA is not a practical solution for the rapid, precise diagnosis of infectious diseases in-the-field.To address this problem, resea...
|
 |
|
|
|
|
University of California, Berkeley
|
BioMEMS Immunoassay Platform for In-Field Diagnostics
|
|
|
The rapid diagnosis of infectious diseases is critical for quick containment and effective treatment. The dominant diagnostics technology, ELISA, is cost-effective for diagnosing diseases in a hospital or doctor's office with a laboratory and trained staff. However, ELISA is not a practical solution for the rapid, precise diagnosis of infectious diseases in-the-field.To address this problem, resea...
|
 |
|
|
|
|
University of California, Berkeley
|
BioMEMS Immunoassay Platform for In-Field Diagnostics
|
|
|
The rapid diagnosis of infectious diseases is critical for quick containment and effective treatment. The dominant diagnostics technology, ELISA, is cost-effective for diagnosing diseases in a hospital or doctor's office with a laboratory and trained staff. However, ELISA is not a practical solution for the rapid, precise diagnosis of infectious diseases in-the-field.To address this problem, resea...
|
 |
|
|
|
|
University of California, Berkeley
|
Biomimetically Inspired Artificial Compound Eyes
|
|
|
Compound eyes in nature have been one of the most studied and intriguing topics in physiological optics due to their unique optical scheme for imaging. Hundreds to ten thousands of integrated optical units called ommatidia are spherically arranged along a curvilinear surface and point in different directions. Each ommatidium collects light within a small angular acceptance and collectively they co...
|
 |
|
|
|
|
University of California, Berkeley
|
Biomimetically Inspired Artificial Compound Eyes
|
|
|
Compound eyes in nature have been one of the most studied and intriguing topics in physiological optics due to their unique optical scheme for imaging. Hundreds to ten thousands of integrated optical units called ommatidia are spherically arranged along a curvilinear surface and point in different directions. Each ommatidium collects light within a small angular acceptance and collectively they co...
|
 |
|
|
|
|
University of California, Berkeley
|
Biomimetically Inspired Artificial Compound Eyes
|
|
|
Compound eyes in nature have been one of the most studied and intriguing topics in physiological optics due to their unique optical scheme for imaging. Hundreds to ten thousands of integrated optical units called ommatidia are spherically arranged along a curvilinear surface and point in different directions. Each ommatidium collects light within a small angular acceptance and collectively they co...
|
 |
|
|
|
|
University of California, Berkeley
|
Biomimetically Inspired Artificial Compound Eyes
|
|
|
Compound eyes in nature have been one of the most studied and intriguing topics in physiological optics due to their unique optical scheme for imaging. Hundreds to ten thousands of integrated optical units called ommatidia are spherically arranged along a curvilinear surface and point in different directions. Each ommatidium collects light within a small angular acceptance and collectively they co...
|
 |
|
|
|
|
University of California, Berkeley
|
Biomimetically Inspired Artificial Compound Eyes
|
|
|
Compound eyes in nature have been one of the most studied and intriguing topics in physiological optics due to their unique optical scheme for imaging. Hundreds to ten thousands of integrated optical units called ommatidia are spherically arranged along a curvilinear surface and point in different directions. Each ommatidium collects light within a small angular acceptance and collectively they co...
|
 |
|
|
|
|
University of California, Berkeley
|
Biomimetically Inspired Artificial Compound Eyes
|
|
|
Compound eyes in nature have been one of the most studied and intriguing topics in physiological optics due to their unique optical scheme for imaging. Hundreds to ten thousands of integrated optical units called ommatidia are spherically arranged along a curvilinear surface and point in different directions. Each ommatidium collects light within a small angular acceptance and collectively they co...
|
 |
|
|
|
|
University of California, Berkeley
|
Braking Light System for a Vehicle
|
|
|
Apparent motion is created in an object to stimulate rapid M cell response in an observer's visual system. In one embodiment of this invention made at University of California, Berkeley, a vehicle is equipped with at least left and right pairs of brake lights spaced apart about 1 to 60 minutes of visual angle at the viewing distance. Vehicle braking activates the innermost of each pair of lights f...
|
 |
|
|
|
|
University of California, Berkeley
|
Broad Bandwidth and Highly Reflective Gratings
|
|
|
Broadband mirrors with very high reflectivity are essential for applications such as telecommunications, surveillance, sensors and imaging. Among the various conventional mirror designs, metal mirrors have larger reflection bandwidths but lower reflectivities; as a result they are not suitable for fabricating transmission-type optical devices such as etalon filters. Dielectric distributed Bragg re...
|
 |
|
|
|
|
University of California, Berkeley
|
Broad Bandwidth and Highly Reflective Gratings
|
|
|
Broadband mirrors with very high reflectivity are essential for applications such as telecommunications, surveillance, sensors and imaging. Among the various conventional mirror designs, metal mirrors have larger reflection bandwidths but lower reflectivities; as a result they are not suitable for fabricating transmission-type optical devices such as etalon filters. Dielectric distributed Bragg re...
|
 |
|
|
|
|
University of California, Berkeley
|
Broad Bandwidth and Highly Reflective Gratings
|
|
|
Broadband mirrors with very high reflectivity are essential for applications such as telecommunications, surveillance, sensors and imaging. Among the various conventional mirror designs, metal mirrors have larger reflection bandwidths but lower reflectivities; as a result they are not suitable for fabricating transmission-type optical devices such as etalon filters. Dielectric distributed Bragg re...
|
 |
|
|
|
|
University of California, Berkeley
|
Broad Bandwidth and Highly Reflective Gratings
|
|
|
Broadband mirrors with very high reflectivity are essential for applications such as telecommunications, surveillance, sensors and imaging. Among the various conventional mirror designs, metal mirrors have larger reflection bandwidths but lower reflectivities; as a result they are not suitable for fabricating transmission-type optical devices such as etalon filters. Dielectric distributed Bragg re...
|
 |
|
|
|
|
University of California, Berkeley
|
Broad Bandwidth and Highly Reflective Gratings
|
|
|
Broadband mirrors with very high reflectivity are essential for applications such as telecommunications, surveillance, sensors and imaging. Among the various conventional mirror designs, metal mirrors have larger reflection bandwidths but lower reflectivities; as a result they are not suitable for fabricating transmission-type optical devices such as etalon filters. Dielectric distributed Bragg re...
|
 |
|
|
|
|
University of California, Berkeley
|
Broad Bandwidth and Highly Reflective Gratings
|
|
|
Broadband mirrors with very high reflectivity are essential for applications such as telecommunications, surveillance, sensors and imaging. Among the various conventional mirror designs, metal mirrors have larger reflection bandwidths but lower reflectivities; as a result they are not suitable for fabricating transmission-type optical devices such as etalon filters. Dielectric distributed Bragg re...
|
 |
|
|
|
|
University of California, Berkeley
|
Bulk Hydrophilic Imprinted Silica
|
|
|
The objective of molecular imprinting is to create solid materials containing chemical functionalities that are spatially organized by interactions with imprint (or template) molecules during the synthesis process. Subsequent removal of the imprint molecules leaves behind designed sites for the recognition of small molecules, making the material ideally suited for applications such as separations,...
|
 |
|
|
|
|
University of California, Berkeley
|
Bulk Hydrophilic Imprinted Silica
|
|
|
The objective of molecular imprinting is to create solid materials containing chemical functionalities that are spatially organized by interactions with imprint (or template) molecules during the synthesis process. Subsequent removal of the imprint molecules leaves behind designed sites for the recognition of small molecules, making the material ideally suited for applications such as separations,...
|
 |
|
|
|
|
University of California, Berkeley
|
Bulk Hydrophilic Imprinted Silica
|
|
|
The objective of molecular imprinting is to create solid materials containing chemical functionalities that are spatially organized by interactions with imprint (or template) molecules during the synthesis process. Subsequent removal of the imprint molecules leaves behind designed sites for the recognition of small molecules, making the material ideally suited for applications such as separations,...
|
 |
|
|
|
|
University of California, Berkeley
|
Bulk Hydrophilic Imprinted Silica
|
|
|
The objective of molecular imprinting is to create solid materials containing chemical functionalities that are spatially organized by interactions with imprint (or template) molecules during the synthesis process. Subsequent removal of the imprint molecules leaves behind designed sites for the recognition of small molecules, making the material ideally suited for applications such as separations,...
|
 |
|
|
|
|
University of California, Berkeley
|
Bulk Hydrophilic Imprinted Silica
|
|
|
The objective of molecular imprinting is to create solid materials containing chemical functionalities that are spatially organized by interactions with imprint (or template) molecules during the synthesis process. Subsequent removal of the imprint molecules leaves behind designed sites for the recognition of small molecules, making the material ideally suited for applications such as separations,...
|
 |
|
|
|
|
University of California, Berkeley
|
Caged NADP and NAD
|
|
|
The pyridine nucleotides, NAD and NADP, are the most abundant coenzymes in eukaryotic cells. Caged derivatives of NAD and NADP could prove to be an invaluable tool for studying systems utilizing these cofactors where traditional means of rapid mixing are not possible; such as with living cells, tissue slices and protein crystals. As inert compounds, caged systems can be introduced into biological ...
|
 |
|
|
|
|
University of California, Berkeley
|
Caged NADP and NAD
|
|
|
The pyridine nucleotides, NAD and NADP, are the most abundant coenzymes in eukaryotic cells. Caged derivatives of NAD and NADP could prove to be an invaluable tool for studying systems utilizing these cofactors where traditional means of rapid mixing are not possible; such as with living cells, tissue slices and protein crystals. As inert compounds, caged systems can be introduced into biological ...
|
 |
|
|
|
|
University of California, Berkeley
|
Capacitorless, Silicon-on-Insulator DRAM Device
|
|
|
The great commercial success of DRAM can be attributed in large part to the continued miniaturization of the memory cell unit that in turn drives increased storage density and decreased costs.To further improve DRAM memory density, researchers at the University of California, Berkeley have developed a new technology that features a capacitorless DRAM (CDRAM) cell on Silicon-On-Insulator (SOI) subs...
|
 |
|
|
|
|
University of California, Berkeley
|
Capacitorless, Silicon-on-Insulator DRAM Device
|
|
|
The great commercial success of DRAM can be attributed in large part to the continued miniaturization of the memory cell unit that in turn drives increased storage density and decreased costs.To further improve DRAM memory density, researchers at the University of California, Berkeley have developed a new technology that features a capacitorless DRAM (CDRAM) cell on Silicon-On-Insulator (SOI) subs...
|
 |
|
|
|
|
University of California, Berkeley
|
CAVEAT 2.2
|
|
|
Description:The program CAVEAT accomplishes a number of tasks to assist in the structure-based design of molecules:1.Converts a source database of three-dimensional molecular structures, in which the molecules are characterized by the Cartesian coordinates (or their equivalents) of the individual atoms, into a database (called a vector database) in which the molecules are characterized by the geom...
|
 |
|
|
|
|
University of California, Berkeley
|
CAVEAT 2.2
|
|
|
Description:The program CAVEAT accomplishes a number of tasks to assist in the structure-based design of molecules:1.Converts a source database of three-dimensional molecular structures, in which the molecules are characterized by the Cartesian coordinates (or their equivalents) of the individual atoms, into a database (called a vector database) in which the molecules are characterized by the geom...
|
 |
|
|
|
|
University of California, Berkeley
|
Cell Lines and Transgenic Mice containing Fatty Acid Synthase Promoter-Luciferase Constructs
|
|
|
Fatty acids synthase (FAS) plays a central role in de novo lipogenesis in mammals and birds. FAS activities and concentrations in animals' liver and adipose tissues are subjective to nutritional and hormonal manipulations.This disclosure relates to cell lines and transgenic mice containing fatty acid synthase promoter-luciferase constructs.References:D Wang & HS Sul. 1995. Upstream Stimulatory...
|
 |
|
|
|
|
University of California, Berkeley
|
Cell lines for Fusion Partners for T Cell Hybridomas
|
|
|
These cell lines can be used as fusion partners for generating mouse T cell hybridomas. The antigen specific activation response of the T cell hybridomas generated by these cell lines can be measured using either conventional IL-2 assay or assays for the beta-galactosidase enzymatic activity which is specifically induced in these hybridomas. The ability to measure T cell activation using the beta-...
|
 |
|
|
|
|
University of California, Berkeley
|
Cell Surface Engineering/Chemoselective Ligation Reaction
|
|
|
Also see: E. Saxon and C. R. Bertozzi, Cell Surface Engineering By A Modified Staudinger Reaction, Science 2000 Mar. 17: 287 (5460): 2007-2010.Selective chemical reactions enacted within a cellular environment can be powerful tools for elucidating biological processes or engineering novel interactions. A chemical transformation that permits the selective formation of covalent adducts among richly ...
|
 |
|
|
|
|
University of California, Berkeley
|
Cereal Transformation of Using Cultured Organogenic Tissue
|
|
|
A novel transformation method for transforming many commercial genotypes of cereals has been developed. The method incolves using meristematic tissues which include vegetative shoot meristems and young leaf bases as initial explants and the induction of a direct organogenesis pathway for in vitro proliferation and plant regeneration. Use of this pathway results in less impact and destabilizaton of...
|
 |
|
|
|
|
University of California, Berkeley
|
Cereal Transformation of Using Cultured Organogenic Tissue
|
|
|
A novel transformation method for transforming many commercial genotypes of cereals has been developed. The method incolves using meristematic tissues which include vegetative shoot meristems and young leaf bases as initial explants and the induction of a direct organogenesis pathway for in vitro proliferation and plant regeneration. Use of this pathway results in less impact and destabilizaton of...
|
 |
|
|
|
|
University of California, Berkeley
|
Chemical Vapor Deposition and Selective Etching of Silicon Carbide Films
|
|
|
Silicon carbide (SiC) is an ideal material for high-temperature, high-power, and high-voltage electronic devices. SiC also has many additional properties that make it well-suited to microelectromechanical systems (MEMS) that are required to work in harsh environments. While the material is promising, deposition of SiC has only been achieved in high-vacuum, custom-built systems that yield small sam...
|
 |
|
|
|
|
University of California, Berkeley
|
Chemical Vapor Deposition and Selective Etching of Silicon Carbide Films
|
|
|
Silicon carbide (SiC) is an ideal material for high-temperature, high-power, and high-voltage electronic devices. SiC also has many additional properties that make it well-suited to microelectromechanical systems (MEMS) that are required to work in harsh environments. While the material is promising, deposition of SiC has only been achieved in high-vacuum, custom-built systems that yield small sam...
|
 |
|
|
|
|
University of California, Berkeley
|
CHIRAL BUILDING BLOCKS, CATALYSTS AND ORGANIC SYNTHESIS
|
|
|
United States Patent 6,359,174MacMillan , et al. March 19, 2002------------------------------------------------------------------------Lewis acid-catalyzed claisen rearrangement in the preparation of chiral productsAbstractA novel Claisen rearrangement reaction is provided. An allylic reactant such as an allylic amine, an allylic ether or an allylic thioether is reacted with an acid chloride in th...
|
 |
|
|
|
|
University of California, Berkeley
|
Clean Energy Technology Economics and Emissions Model
|
|
|
Intensive research efforts in the field of clean energy technologies, such as fuel cells, are primarily focused on solving technical issues to commercialization. As these technology challenges are resolved, analytical tools will be needed to understand the economic viability and environmental impact of using these emerging energy technologies in different applications.To address the need for these...
|
 |
|
|
|
|
University of California, Berkeley
|
Clean Energy Technology Economics and Emissions Model
|
|
|
Intensive research efforts in the field of clean energy technologies, such as fuel cells, are primarily focused on solving technical issues to commercialization. As these technology challenges are resolved, analytical tools will be needed to understand the economic viability and environmental impact of using these emerging energy technologies in different applications.To address the need for these...
|
 |
|
|
|
|
University of California, Berkeley
|
Cloning and Expression of Yeast STE13 and DPP2 Genes Encoding Dipeptidyl Aminopeptidase A and B
|
|
|
A method is provided for expressing the proteases dipeptidyl aminopeptidases A and B which are useful for processing precursor proteins. Genes contolling these proteases may be inserted into appropriate vectors and transformed into cultures. The proteases may either be utilized to process precursor proteins in vivo or may be extracted from cultures and used to process precursor proteins in vitro....
|
 |
|
|
|
|
University of California, Berkeley
|
Closed-Gas Power Cycle for Liquid Metal and Molten Salt-Cooled Reactors
|
|
|
Research at the University of California, Berkeley has led to the development of an innovative approach that addresses the material issues which have traditionally prevented the use of closed gas power cycles with liquid metal and molten salt coolants. Design calculations that apply these innovations have shown that cycle thermal efficiencies comparable to current helium-cooled reactor designs (&g...
|
 |
|
|
|
|
University of California, Berkeley
|
Closed-Gas Power Cycle for Liquid Metal and Molten Salt-Cooled Reactors
|
|
|
Research at the University of California, Berkeley has led to the development of an innovative approach that addresses the material issues which have traditionally prevented the use of closed gas power cycles with liquid metal and molten salt coolants. Design calculations that apply these innovations have shown that cycle thermal efficiencies comparable to current helium-cooled reactor designs (&g...
|
 |
|
|
|
|
University of California, Berkeley
|
Cognitive Assessment Monitor
|
|
|
Systems to continuously assess cognitive capabilities would be of benefit to a wide range of individuals, such as diabetics under hypoglycemic risk, Alzheimer's disease patients, for evaluation of neuro-toxicology effects, and for persons performing potentially dangerous tasks such as driving a car or piloting a plane. The results from the continuous cognitive assessment could be employed, for ins...
|
 |
|
|
|
|
University of California, Berkeley
|
Cognitive Assessment Monitor
|
|
|
Systems to continuously assess cognitive capabilities would be of benefit to a wide range of individuals, such as diabetics under hypoglycemic risk, Alzheimer's disease patients, for evaluation of neuro-toxicology effects, and for persons performing potentially dangerous tasks such as driving a car or piloting a plane. The results from the continuous cognitive assessment could be employed, for ins...
|
 |
|
|
|
|
University of California, Berkeley
|
Cognitive Assessment Monitor
|
|
|
Systems to continuously assess cognitive capabilities would be of benefit to a wide range of individuals, such as diabetics under hypoglycemic risk, Alzheimer's disease patients, for evaluation of neuro-toxicology effects, and for persons performing potentially dangerous tasks such as driving a car or piloting a plane. The results from the continuous cognitive assessment could be employed, for ins...
|
 |
|
|
|
|
University of California, Berkeley
|
Cognitive Assessment Monitor
|
|
|
Systems to continuously assess cognitive capabilities would be of benefit to a wide range of individuals, such as diabetics under hypoglycemic risk, Alzheimer's disease patients, for evaluation of neuro-toxicology effects, and for persons performing potentially dangerous tasks such as driving a car or piloting a plane. The results from the continuous cognitive assessment could be employed, for ins...
|
 |
|
|
|
|
University of California, Berkeley
|
Combinatorial Purine Libraries as Inhibitors of Cyclin Dependent Kinases
|
|
|
Abstract:Selective protein kinase inhibitors were developed on the basis of the unexpected binding mode of 2,6,9-trisubstituted purines to the adenosine triphosphate-binding site of the human cyclin-dependent kinase 2 (CDK2). By iterating chemical library synthesis and biological screening, potent inhibitors of the human CDK2-cyclin A kinase complex and of Saccharomyces cerevisiae Cdc28p were iden...
|
 |
|
|
|
|
University of California, Berkeley
|
Combinatorial Purine Libraries as Inhibitors of Cyclin Dependent Kinases
|
|
|
Abstract:Selective protein kinase inhibitors were developed on the basis of the unexpected binding mode of 2,6,9-trisubstituted purines to the adenosine triphosphate-binding site of the human cyclin-dependent kinase 2 (CDK2). By iterating chemical library synthesis and biological screening, potent inhibitors of the human CDK2-cyclin A kinase complex and of Saccharomyces cerevisiae Cdc28p were iden...
|
 |
|
|
|
|
University of California, Berkeley
|
Combinatorial Purine Libraries for Drug Discovery
|
|
|
The purine ring system is a key structural element of the substrates and ligands of many biosynthetic, regulatory, and signal transduction proteins including cellular kinases, G proteins, and polymerases. Consequently, combinatorial libraries based on this scaffold should facilitate the search for inhibitors of many biomedically significant processes. Here, UC Berkeley scientists have developed li...
|
 |
|
|
|
|
University of California, Berkeley
|
Combinatorial Purine Libraries for Drug Discovery
|
|
|
The purine ring system is a key structural element of the substrates and ligands of many biosynthetic, regulatory, and signal transduction proteins including cellular kinases, G proteins, and polymerases. Consequently, combinatorial libraries based on this scaffold should facilitate the search for inhibitors of many biomedically significant processes. Here, UC Berkeley scientists have developed li...
|
 |
|
|
|
|
University of California, Berkeley
|
Combinatorial Purine Libraries for Drug Discovery
|
|
|
The purine ring system is a key structural element of the substrates and ligands of many biosynthetic, regulatory, and signal transduction proteins including cellular kinases, G proteins, and polymerases. Consequently, combinatorial libraries based on this scaffold should facilitate the search for inhibitors of many biomedically significant processes. Here, UC Berkeley scientists have developed li...
|
 |
|
|
|
|
University of California, Berkeley
|
Compositions and Methods For Plant Pathogen Resistance
|
|
|
Researchers at the University of California at Berkeley have identified a plant resistance gene family, the members of which encode plant resistance polypeptides having P-Loop and LRR structural motifs. This resistance gene class includes Prf, RPS2, RPM1, N, and L6 and represents a large fraction of known plant disease resistance genes. The invention further involves transgenic plants and transfor...
|
 |
|
|
|
|
University of California, Berkeley
|
Compositions and Methods For Plant Pathogen Resistance
|
|
|
Researchers at the University of California at Berkeley have identified a plant resistance gene family, the members of which encode plant resistance polypeptides having P-Loop and LRR structural motifs. This resistance gene class includes Prf, RPS2, RPM1, N, and L6 and represents a large fraction of known plant disease resistance genes. The invention further involves transgenic plants and transfor...
|
 |
|
|
|
|
University of California, Berkeley
|
Compositions and Methods For Plant Pathogen Resistance
|
|
|
Researchers at the University of California at Berkeley have identified a plant resistance gene family, the members of which encode plant resistance polypeptides having P-Loop and LRR structural motifs. This resistance gene class includes Prf, RPS2, RPM1, N, and L6 and represents a large fraction of known plant disease resistance genes. The invention further involves transgenic plants and transfor...
|
 |
|
|
|
|
University of California, Berkeley
|
Construction Analysis for Pavement Rehabilitation Stategies (CA4PRS)
|
|
|
Researchers at the University of California, Berkeley have developed simulation software to carry out a constructability analysis for highway rehabilitation and reconstruction projects. This software interactively links factors such as rehabilitation materials, design profiles, curing/cooling time, number and capacity of construction resources, type of construction scheduling, and alternative lane...
|
 |
|
|
|
|
University of California, Berkeley
|
Continuous Laminar Fluid Mixing Process
|
|
|
Conventional methods for mixing fluids usually involve generating turbulence. Such methods are not appropriate to microfluidic devices since turbulence is extremely hard to achieve at such small scales. Prior art methods for microfluidic mixing using three dimensional flow fields are difficult and expensive to implement since most microfabrication techniques are inherently planar. Other planar, la...
|
 |
|
|
|
|
University of California, Berkeley
|
Continuous Laminar Fluid Mixing Process
|
|
|
Conventional methods for mixing fluids usually involve generating turbulence. Such methods are not appropriate to microfluidic devices since turbulence is extremely hard to achieve at such small scales. Prior art methods for microfluidic mixing using three dimensional flow fields are difficult and expensive to implement since most microfabrication techniques are inherently planar. Other planar, la...
|
 |
|
|
|
|
University of California, Berkeley
|
Continuous Laminar Fluid Mixing Process
|
|
|
Conventional methods for mixing fluids usually involve generating turbulence. Such methods are not appropriate to microfluidic devices since turbulence is extremely hard to achieve at such small scales. Prior art methods for microfluidic mixing using three dimensional flow fields are difficult and expensive to implement since most microfabrication techniques are inherently planar. Other planar, la...
|
 |
|
|
|
|
University of California, Berkeley
|
Countour-Mode Piezoelectric Resonators
|
|
|
There is a growing demand in wireless communications for miniaturized, low-power, low-cost on-chip, high-Q resonators for use in front-end RF filters or as frequency references. This market need has spurred research into new vibrating micromechanical structures that can replace existing off-chip, bulky resonator technologies.In pursuing this market need, researchers at UC Berkeley have developed a...
|
 |
|
|
|
|
University of California, Berkeley
|
Countour-Mode Piezoelectric Resonators
|
|
|
There is a growing demand in wireless communications for miniaturized, low-power, low-cost on-chip, high-Q resonators for use in front-end RF filters or as frequency references. This market need has spurred research into new vibrating micromechanical structures that can replace existing off-chip, bulky resonator technologies.In pursuing this market need, researchers at UC Berkeley have developed a...
|
 |
|
|
|
|
University of California, Berkeley
|
Crystallographic Alignment of High-Density Gallium Nitride Nanowire Arrays
|
|
|
Single-crystalline, one-dimensional semiconductor nanostructures are one of the critical building blocks for nanoscale optoelectronics. Research has demonstrated precise control over nanowire position and size, but to date no reports have been made demonstrating control over crystallographic growth direction of nanowire arrays. Control over nanowire growth direction is very desirable in that aniso...
|
 |
|
|
|
|
University of California, Berkeley
|
Crystallographic Alignment of High-Density Gallium Nitride Nanowire Arrays
|
|
|
Single-crystalline, one-dimensional semiconductor nanostructures are one of the critical building blocks for nanoscale optoelectronics. Research has demonstrated precise control over nanowire position and size, but to date no reports have been made demonstrating control over crystallographic growth direction of nanowire arrays. Control over nanowire growth direction is very desirable in that aniso...
|
 |
|
|
|
|
University of California, Berkeley
|
DETECTION OF HOMOLOGOUS RECOMBINATION EVENTS BY ACTIVATION OF A CHIMERIC REPORTER GENE
|
|
|
Researchers at UC Berkeley have developed a method to simplify identification of meiotic unequal crossing-over of genes in a tandem array or from a multiple transgenic insertion . A synthetic RBCSB gene cluster was produced with a silent RBCS1B::LUC chimeric gene fusion, lacking all 5 transcription and translation signals, followed by RBCS2B and RBC3B genomic DNA. Expression of luciferase activity...
|
 |
|
|
|
|
University of California, Berkeley
|
Devices Using High Temperature Superconductors Disposed on a Chip
|
|
|
The present invention relates generally to microwave and millimeter-wave devices such as antennas and cavities, and more particularly to microwave and millimeter-wave devices using chips including high-temperature superconducting films.The invention is directed to a structure exposed to electromagnetic radiation. The structure comprises discrete elements including a substrate on which a high-tempe...
|
 |
|
|
|
|
University of California, Berkeley
|
Differential Internal Electrostatic Transduction Resonators
|
|
|
Multiple resonators that have different frequencies are essential in the design of micromechanical filters, oscillators and mixers. The commercial potential of these resonators has advanced with the recent development of internal electrostatic transduction structures for lateral high frequency MEMS resonators (see case B04-051).To take further advantage of this commercial potential, researchers at...
|
 |
|
|
|
|
University of California, Berkeley
|
Differential Internal Electrostatic Transduction Resonators
|
|
|
Multiple resonators that have different frequencies are essential in the design of micromechanical filters, oscillators and mixers. The commercial potential of these resonators has advanced with the recent development of internal electrostatic transduction structures for lateral high frequency MEMS resonators (see case B04-051).To take further advantage of this commercial potential, researchers at...
|
 |
|
|
|
|
University of California, Berkeley
|
DNA Complexes with Dyes Designed for Energy Transfer as Fluorescent Reagents
|
|
|
Heteromultimeric fluorophores are provided for binding to DNA, which allow for detection of DNA in electrical separations and preparation of probes having high fluorescent molecules, one can use a single narrow wavelength band excitation light source, while obtaining fluorescent emissions having sufficient separation to be readily discriminated....
|
 |
|
|
|
|
University of California, Berkeley
|
DNA RECOMBINATION IN EUKARYOTIC CELLS BY THE BACTERIOPHAGE PHIC31 RECOMBINATION SYSTEM
|
|
|
This invention provides methods for obtaining specific and stable integration of nucleic acids into eukaryotic cells. The method is an alternative to the widely used CRE-LOX method.The invention makes use of site-specific recombination systems that use prokaryotic recombinase polypeptides, such as the phiC31 recombinase, that can mediate recombination between the recombination sites, but not betwe...
|
 |
|
|
|
|
University of California, Berkeley
|
DNA RECOMBINATION IN EUKARYOTIC CELLS BY THE BACTERIOPHAGE PHIC31 RECOMBINATION SYSTEM
|
|
|
This invention provides methods for obtaining specific and stable integration of nucleic acids into eukaryotic cells. The method is an alternative to the widely used CRE-LOX method.The invention makes use of site-specific recombination systems that use prokaryotic recombinase polypeptides, such as the phiC31 recombinase, that can mediate recombination between the recombination sites, but not betwe...
|
 |
|
|
|
|
University of California, Berkeley
|
DNA RECOMBINATION IN EUKARYOTIC CELLS BY THE BACTERIOPHAGE PHIC31 RECOMBINATION SYSTEM
|
|
|
This invention provides methods for obtaining specific and stable integration of nucleic acids into eukaryotic cells. The method is an alternative to the widely used CRE-LOX method.The invention makes use of site-specific recombination systems that use prokaryotic recombinase polypeptides, such as the phiC31 recombinase, that can mediate recombination between the recombination sites, but not betwe...
|
 |
|
|
|
|
University of California, Berkeley
|
Dominant Negative Nur77 Gene Inhibitor of Apoptosis
|
|
|
Apoptosis is a phenomenon observed during development of many cell types in many organisms. It is an internal, programmed cell death characterized by DNA fragmentation into nucleosome-size pieces. Anti-CD3-induced apoptosis in T-cell hybridomas and immature thymocytes requires new gene transcription and may be related to negative selection during T-cell development. Using subtractive hybridization...
|
 |
|
|
|
|
University of California, Berkeley
|
Dominant Negative Nur77 Gene Inhibitor of Apoptosis
|
|
|
Apoptosis is a phenomenon observed during development of many cell types in many organisms. It is an internal, programmed cell death characterized by DNA fragmentation into nucleosome-size pieces. Anti-CD3-induced apoptosis in T-cell hybridomas and immature thymocytes requires new gene transcription and may be related to negative selection during T-cell development. Using subtractive hybridization...
|
 |
|
|
|
|
University of California, Berkeley
|
Dual Work Function CMOS Gate Technology Based on Metal Interdiffusion
|
|
|
Researchers at the University of California, Berkeley have developed a new metal-gate CMOS technology that uses a combination of two metals to achieve a low threshold voltage for both n- and p-MOSFETs. One of the gate electrodes is formed by metal interdiffusion so that no metal has to be etched away from the gate dielectric surface. Consequently, the process does not compromise the integrity and ...
|
 |
|
|
|
|
University of California, Berkeley
|
Dyes Designed for High Sensitivity Detection of Double-Stranded DNA
|
|
|
Novel fluorescent dyes are provided, characterized by having a fluorophore joined to a polycationic chain of at least two positive charges. The dyes are found to provide for high enhancement upon binding to nucleic acid and have strong binding affinities to the nucleic acid, as compared to the fluorophore without the polycationic chain....
|
 |
|
|
|
|
University of California, Berkeley
|
Dynamic Threshold Voltage MOSFET with a Gate-to-Body Connection for Ultra-Low Voltage Operation
|
|
|
Silicon-on-insulator (SOI) technology offers great promise for ultra large scale integrated circuits using sub-micron gate technology. However, in SOI MOSFETs, the monocrystalline silicon film is often unbiased or floating. Consequently, voltages typically larger than 0.6 volt are required to operate the device, and this exceeds the low-power requirements of the market.To address this problem, res...
|
 |
|
|
|
|
University of California, Berkeley
|
Efficient and Accurate Undercut Detection System
|
|
|
Molding and casting of parts can be done more simply and economically for parts that are free from undercut features, primarily because a more expensive multi-piece mold must be used for parts with such undercut features. Therefore immediate feedback to the designer about the presence of costly undercuts allows for their early removal in the design process. Without immediate and accurate feedback ...
|
 |
|
|
|
|
University of California, Berkeley
|
Efficient and Accurate Undercut Detection System
|
|
|
Molding and casting of parts can be done more simply and economically for parts that are free from undercut features, primarily because a more expensive multi-piece mold must be used for parts with such undercut features. Therefore immediate feedback to the designer about the presence of costly undercuts allows for their early removal in the design process. Without immediate and accurate feedback ...
|
 |
|
|
|
|
University of California, Berkeley
|
Efficient and Accurate Undercut Detection System
|
|
|
Molding and casting of parts can be done more simply and economically for parts that are free from undercut features, primarily because a more expensive multi-piece mold must be used for parts with such undercut features. Therefore immediate feedback to the designer about the presence of costly undercuts allows for their early removal in the design process. Without immediate and accurate feedback ...
|
 |
|
|
|
|
University of California, Berkeley
|
Efficient and Accurate Undercut Detection System
|
|
|
Molding and casting of parts can be done more simply and economically for parts that are free from undercut features, primarily because a more expensive multi-piece mold must be used for parts with such undercut features. Therefore immediate feedback to the designer about the presence of costly undercuts allows for their early removal in the design process. Without immediate and accurate feedback ...
|
 |
|
|
|
|
University of California, Berkeley
|
Efficient Cryptographic System for Public-Key Cryptosystems
|
|
|
Public-key cryptosystems use cryptographic methods to encode and decode messages. The cryptographic methods are designed to be difficult to break, but the most secure cryptographs have large key sizes and wasteful encoding processes that make them impractical to commercially implement.To address this issue, researchers at UC Berkeley have developed a new cryptosystem that is provably hard to break...
|
 |
|
|
|
|
University of California, Berkeley
|
Efficient Cryptographic System for Public-Key Cryptosystems
|
|
|
Public-key cryptosystems use cryptographic methods to encode and decode messages. The cryptographic methods are designed to be difficult to break, but the most secure cryptographs have large key sizes and wasteful encoding processes that make them impractical to commercially implement.To address this issue, researchers at UC Berkeley have developed a new cryptosystem that is provably hard to break...
|
 |
|
|
|
|
University of California, Berkeley
|
Efficient Cryptographic System for Public-Key Cryptosystems
|
|
|
Public-key cryptosystems use cryptographic methods to encode and decode messages. The cryptographic methods are designed to be difficult to break, but the most secure cryptographs have large key sizes and wasteful encoding processes that make them impractical to commercially implement.To address this issue, researchers at UC Berkeley have developed a new cryptosystem that is provably hard to break...
|
 |
|
|
|
|
University of California, Berkeley
|
Efficient Cryptographic System for Public-Key Cryptosystems
|
|
|
Public-key cryptosystems use cryptographic methods to encode and decode messages. The cryptographic methods are designed to be difficult to break, but the most secure cryptographs have large key sizes and wasteful encoding processes that make them impractical to commercially implement.To address this issue, researchers at UC Berkeley have developed a new cryptosystem that is provably hard to break...
|
 |
|
|
|
|
University of California, Berkeley
|
Efficient Cryptographic System for Public-Key Cryptosystems
|
|
|
Public-key cryptosystems use cryptographic methods to encode and decode messages. The cryptographic methods are designed to be difficult to break, but the most secure cryptographs have large key sizes and wasteful encoding processes that make them impractical to commercially implement.To address this issue, researchers at UC Berkeley have developed a new cryptosystem that is provably hard to break...
|
 |
|
|
|
|
University of California, Berkeley
|
Efficient On-Chip Sample Preparation
|
|
|
In conventional chemical and biological analysis the most time consuming and expensive steps involve sample preparation. Preparation of biological samples for on-chip analysis requires extraction of intracellular biomolecules, accomplished by various methods of cell lysis. Depending on the type of analysis to be performed, lysing may be done with detergents, thermal cycling, or irreversible electr...
|
 |
|
|
|
|
University of California, Berkeley
|
Efficient On-Chip Sample Preparation
|
|
|
In conventional chemical and biological analysis the most time consuming and expensive steps involve sample preparation. Preparation of biological samples for on-chip analysis requires extraction of intracellular biomolecules, accomplished by various methods of cell lysis. Depending on the type of analysis to be performed, lysing may be done with detergents, thermal cycling, or irreversible electr...
| |